Gaspar Juan Pérez de Guzmán y Guzmán, 10th Duke of Medina Sidonia (1630–1667) was Duke of Medina Sidonia from 1664 to 1667. He died without issue, and the title passed to his younger half brother.
| Spanish nobility | ||
|---|---|---|
| Preceded by Gaspar Alfonso Pérez de Guzmán |
Duke of Medina Sidonia 1664–1667 |
Succeeded by Juan Claros Pérez de Guzmán |